Complement C3c 抗体
Quick Overview for Complement C3c 抗体 (ABIN206657)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes 135kD complement component 3c (C3c), present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha chain fragment 1 + alpha chain fragment 2), C3dg and C3f. C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation. Binds both C3c and C3 and so is not suitable for all ELISA applications.
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纯化方法
- Protein A purified
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免疫原
- Native human C3 from normal serum, highly purified by chromatography.
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亚型
- IgG1
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anti-Complement Component C3c (C3C) (AA 1521-1649) antibody
C3C 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 8B5H2 unconjugated
anti-Complement Component C3c (C3C) (AA 1521-1649) antibodyC3C 适用: 人 ELISA, WB, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4C6A8 unconjugated
anti-Complement Component C3c (C3C) antibodyC3C 适用: 人 IHC (p), ID 宿主: 山羊 Polyclonal unconjugated
anti-Complement Component C3c (C3C) antibodyC3C 适用: 人 ELISA, IHC, IHC (fro), IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Complement Component C3c (C3C) antibodyC3C 适用: 人 IHC (p), ID 宿主: 兔 Polyclonal unconjugated
anti-Complement Component C3c (C3C) (AA 1051-1200) antibodyC3C 适用: 人, 大鼠, Pig ELISA, WB, ICC, IF (p), IF (cc), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Approved: ELISA, Flo, IHC, IHC-Fr, WB
Usage: ELISA: LS-C44974 binds both C3c and C3 and so is not suitable for all ELISA applications. Western Blot: LS-C44974 binds both C3c and C3 and so is not suitable for all ELISA applications. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline, 0.1 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
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- Complement C3c (C3C) (Complement Component C3c (C3C))
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别名
- Complement C3/C3c
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UniProt
- P01024
抗原
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